Abstract
Bacterial infection is one of the main reasons for the long-term failure of orthopedic implants. Despite remarkable progression in antimicrobial drugs, implant-associated infection (IAI) remains difficult to treat, which is resulted from bacterial resistance against antibiotics. As a result, there is an urgent need to develop alternative approaches. The present review highlights surface modification of the orthopedic implants as a promising approach to inhibit bacterial infection. This approach can be classified into two groups: (1) bacteriostatic (anti-adhesive), and (2) bactericidal (contact-killing/release-killing) surfaces. Their combination, which is considered as bacteriostatic-bactericidal bi-functional surface, can provide a more robust approach against dangerous pathogenic species. New approaches and future perspectives in this inspiring field are also provided.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
