Surface components of Campylobacter and Helicobacter.

Abstract

The major components of the surfaces of Helicobacter pylori and Campylobacter jejuni are considered in turn, comparing and contrasting where possible the key features of each organism. The components considered are the outer membrane, including protein as well as polysaccharide components; the S-layer proteins of Campylobacter fetus and Campylobacter rectus; and the flagella of both organisms including the regulation of flagellar gene expression. Proteins secreted by these organisms are also considered. In conclusion, it is clear that the unique pathogenic properties of these closely related organisms are dependent to a large extent on key differences in their surface components.