Abstract
Suppressive Effects of Aqueous Extracts of Neem (Melia Azadirachta L.) on Some Initial Growth Parameters of Cow Pea & Horse GramA. Kanaga, P. Muniyammal, R. Manonmani
Highlights
The abnormal functioning of the immune system leads to several chronic illnesses and protection of immune system using plant compounds or plant extracts is in recent times getting renewed interest because of their minimal side effects
The scanning electron micrograph of splenic macrophages isolated from the respective groups showed that CCl4 intoxication somehow render the differentiation of splenic macrophages and because of that CCl4 intoxicated splenic macrophages were deficient of pseudopods as compared to control groups
Administration of aqueous extract of T. cordifolia retained the normal morphology as well as reduces the presence of undifferentiated macrophages in spleen isolated from CCl4 intoxicated male albino mice
Summary
The abnormal functioning of the immune system leads to several chronic illnesses and protection of immune system using plant compounds or plant extracts is in recent times getting renewed interest because of their minimal side effects. Alternative to allopathic medicine to support the immune system, we opted for Tinospora cordifolia (T. cordifolia, Menispermaceae) belonging from a group of medicinal plants that grows in the tropical and subtropical regions of India. This herb is extensively used in the Indian System of Medicine; the extract of different parts of the herb has found wide use in a variety of diseases (Aranha et al, 2012; Sharma et al, 2010). CCl4-induced immunotoxicity and amelioration of such immunosuppressive effects by T. cordifolia in splenic macrophages have been further elucidated in the present study
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