Abstract
This study aims to prove that supplementation of red bean extract (Phaseolus vulgaris L) decreased malondialdehyde (MDA) levels of stressly induced activity of male wistar rats (Rattus norvegicus). This research was an experimental with pre-test post-test control group design. The rats were randomly divides into 3 groups: negatif control group (P0), positive control group (treated with overtraining and aquades 2ml/P1), and treatment group (treated with supllementation of red bean extract 650 mg/200 g body weight and overtraining/P2). The rats were swam for 45 minutes everyday. Data were analysed by one way anova test. The study showed that MDA level pretest of the each group was 69,70±0,52 mmol/L; 70,12±0,54 mmol/L and 69,59±0,51 mmol/L respectively. MDA level posttest of the each group was 69,66±0,27 mmol/L; 90,08±0,20 mmol/L and 62,85±0,50 mmol/L respectively. From the result of this study, it can be concluded that suplementation of red bean extract (Phaseolus vulgaris L) decreased malondialdehyde (MDA) levels of stressly induced activity of male wistar rats (Rattus norvegicus).
 Keyword: red bean (Phaseolus vulgaris L) extract, rats, overtraining, MDA, stress oxidative.
Highlights
Decreased malondialdehyde (MDA) levels of stressly induced activity of male wistar rats (Rattus norvegicus)
This study aims to prove that supplementation of red bean extract (Phaseolus vulgaris L)
KESIMPULAN Berdasarkan hasil penelitian ini, disimpulkan bahwa pemberian ekstrak kacang merah peroral dengan dosis 650 mg/200g BB tikus/hari secara oral dapat menurunkan kadar MDA pada tikus yang diberikan aktivitas fisik berlebih
Summary
Decreased malondialdehyde (MDA) levels of stressly induced activity of male wistar rats (Rattus norvegicus). Aktivitas fisik berlebih yang dilakukan akan menimbulkan stres oksidatif sehinga dapat meningkatkan konsumsi oksigen sampai 100200 kali lipat karena terjadi peningkatan metabolisme di dalam tubuh. Stress oksidatif yang disebabkan aktivitas fisik berlebih menyebabkan perlunya peningkatan konsumsi antioksidan untuk melindungi tubuh. Peneliti ingin mengetahui fungsi ekstrak kacang merah sebagai antioksidan dalam menurunkan kadar Malondialdehyde (MDA) pada darah tikus Wistar (Rattus norvegicus) yang diberikan aktivitas fisik berlebih.
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