Abstract
Supplementation of Lactobacillus Probiotic Strains Supports Gut- Brain-Axis and Defends Autistic Deficits Occurred by Valproic Acid-Induced Prenatal Model of Autism
Highlights
Autism is a chronic neurodevelopmental disorder manifested by complex neurobehavioral conditions.[1]
Prebiotics and probiotics and fecal microbiota transplantation are the various therapeutic opportunities.[7,11]. Probiotics, such as the lactic acid-producing bacteria belonging to Lactobacilli, Bifidobacteria and Saccharomycetes, are beneficial to the host when we provided in adequate quantities.[12,13]
There was a significant increase in time taken to re-orient along the inclined plane seen in autistic group on postnatal day (PND) 9-21, when compared to vehicle group (p
Summary
Autism is a chronic neurodevelopmental disorder manifested by complex neurobehavioral conditions.[1]. Gut and brain have bidirectional communication through the enteric nervous system (ENS) and vagus nerves Such interactions can be mediated by the metabolites produced by gut bacteria called short chain fatty acids (SCFA).[5,6] The human gut is inhabited by more than a trillion Prebiotics and probiotics and fecal microbiota transplantation are the various therapeutic opportunities.[7,11] Probiotics, such as the lactic acid-producing bacteria belonging to Lactobacilli, Bifidobacteria and Saccharomycetes, are beneficial to the host when we provided in adequate quantities.[12,13] Many studies have shown that probiotics can prevent and treat a variety of diseases, such as obesity, depression, colorectal cancer and Crohn's disease, in animal models and humans.[14,15].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
