Recent advances and future perspective in microbiota and probiotics.

Haruki Kitazawa,Borja Sánchez,Julio Villena,Vyacheslav Melnikov,Susana Alvarez,Alexander Suvorov

doi:10.1155/2015/275631

Abstract

Recent advances and future perspective in microbiota and probiotics.

Highlights

Studies have provided insight into the mechanisms by which probiotic bacteria are able to regulate the colonization and eradication of pathogens in the gut, including competition for limited nutrients in the intestine and modulation of the mucosal immune system [4, 5]
The work could set the basis for developing systems for early detection of inflammatory bowel diseases (IBDs), based on the association of high levels of antibodies developed against extracellular proteins from lactic acid bacteria
The authors showed in intestinal epithelial cells cultures and in a DSS colitis mouse model that the probiotic strain Lf1 was able to increase the expression of antioxidative enzymes and reduce colitis, indicating that probiotics could be explored as a new strategy for IBD management through activation of the antioxidant enzyme system

Summary

Introduction

Studies have provided insight into the mechanisms by which probiotic bacteria are able to regulate the colonization and eradication of pathogens in the gut, including competition for limited nutrients in the intestine and modulation of the mucosal immune system [4, 5]. There is a growing body of evidence to support the potential use of selected bacterial strains in the prevention and treatment of various human and animal diseases.

Results

Conclusion