Supplementary Tables from Single-Nucleotide Polymorphisms in Vitamin D–Related Genes May Modify Vitamin D–Breast Cancer Associations

Abstract

<p>Supplementary Table 1. Between SNP correlations (r2) for VDR SNPs among sub-cohort sample from the Sister Study (n=1829); Supplementary Table 2. Joint effects of 25(OH)D and single nucleotide polymorphisms (SNPs) in vitamin D metabolism genes on the 5-year risk of post-menopausal breast cancer: Ratio of hazard ratios and 95% confidence intervals; Supplementary Table 3. Joint effects of 25(OH)D and single nucleotide polymorphisms (SNPs) in vitamin D metabolism genes on the 5-year risk of breast cancer according to first-degree family history: Minor allele frequencies (MAFs), Ratio of hazard ratios (RHR), 95% confidence intervals (95% CI), and interaction p-values (top 12 SNPs only); Supplementary Table 4. Top hits for joint effects of 25(OH)D and single nucleotide polymorphisms (SNPs) in other vitamin D-related genes on the 5-year risk of breast cancer; Supplementary Table 5. Gene-environment set association tests (GESAT) for 25(OH)D and other vitamin D-related genes on the 5-year risk of breast cancer</p>