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Abstract
Prostate cancer (PCa) is the most frequent tumor in men worldwide. PCa bone metastasis is mainly osteosclerotic, and is caused by a relative excess of osteoblast activity. A superscan on Tc-99m bone scintigraphy is described in multiple skeletal metastatic disease. Prostate-specific membrane antigen (PSMA) is a cell surface protein with high expression in prostate carcinoma cells. Ga-68 labelled PSMA imaging is used for staging and to evaluate the most appropriate therapy.
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