Abstract

This work investigates supercritical fluid extraction of secondary metabolites from a brown marine alga of Dictyotales species Dilophus ligulatus. In the first part, supercritical carbon dioxide extraction is compared to organic solvents extraction, on the basis of yields, results of chromatographic analysis and inhibiting activities of the growth of a human pathogenic fungus. In the second part, carbon dioxide extraction by stagewise pressure increase is described. Results allow us to conclude that supercritical extraction is a conceivable process to obtain several active compounds from marine organisms and it will also compete favorably with liquid extraction.

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