Abstract
Traditional clinical markers of renal function are unreliable in people with early diabetic kidney disease (DKD). Diffusion tensor imaging (DTI) has potential to non-invasively measure kidney function in early kidney disease, reflecting changes in tubular microstructure. Changes in cortical fractional anisotropy (cFA), medullary fractional anisotropy (mFA) cortical mean diffusivity (cMD) and medullary mean diffusivity (mMD) have been reported in people with type 2 diabetes (T2DM), including people with normal renal function.
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