Abstract
AbstractSulfate is an inert molecule that must be chemically activated before it can be involved in biochemical pathways. This article deals with biological sulfate activation via adenylylation. The activation of inorganic sulfate involves the formation of a “high energy” phosphosulfate anhydride bond in adenosine‐5′‐phosphosulfate (APS) and is catalyzed by the enzyme ATP sulfurylase. A consecutive step, catalyzed by APS kinase, produces another form of activated sulfate: 3′‐phosphoadenosine 5′‐phosphosulfate (PAPS). APS and PAPS are used in the formation of the thiol groups of sulfur containing amino acids and their derivatives, as well as specialized sulfur compounds, and also have other diverse functions.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
