Abstract
BackgroundCaffeine is a widely used dietary stimulant, and cases of caffeine overdoses, sometimes leading to death, are increasing. We encountered a case of caffeine intoxication resolved with administration of the sedative agent dexmedetomidine.Case presentationWe administered dexmedetomidine for sedation and to suppress sympathetic nerve stimulation in the case of an 18-year-old Japanese male who ingested a massive dose of caffeine with the intention of committing suicide. The patient was in an excited state and had hypertension, sinus tachycardia, and hypokalemia with prominent QT prolongation. After dexmedetomidine administration, the patient’s mental state, hemodynamics, and electrolyte levels were improved immediately. He was discharged without any sequelae 3 days later.ConclusionCases of acute caffeine intoxication with agitation, sympathetic overactivity and adverse cardiac events would benefit with dexmedetomidine treatment.
Highlights
Caffeine is a widely used dietary stimulant, and cases of caffeine overdoses, sometimes leading to death, are increasing
Cases of acute caffeine intoxication with agitation, sympathetic overactivity and adverse cardiac events would benefit with dexmedetomidine treatment
Caffeine is ingested through food and drink daily and overdoses have become more likely due to the recent spread of energy drinks and sleepiness-prevention medicines [1]
Summary
Caffeine is a widely used dietary stimulant, and cases of caffeine overdoses, sometimes leading to death, are increasing. Conclusion: Cases of acute caffeine intoxication with agitation, sympathetic overactivity and adverse cardiac events would benefit with dexmedetomidine treatment. Background Caffeine is ingested through food and drink daily and overdoses have become more likely due to the recent spread of energy drinks and sleepiness-prevention medicines [1]. Death from caffeine intoxication in Japan was first reported in 2015, and there is concern that its incidence will increase [2].
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