Abstract
Gymnemic acids, a mixture of triterpene glucuronides extracted from the Indian plant Gymnema sylvestre, have been known to suppress the sweet taste sensation in man. Recent studies have revealed that gymnemic acids showed inhibitory effects not only on glucose absorption in the rat small intestine, but also on glucan synthesis by glucosyltransferase from Streptococcus mutans. These findings suggest that gymnemic acids interact with various proteins which take part in sugar discriminations.
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