SU‐F‐T‐54: Determination of the AAPM TG‐43 Brachytherapy Dosimetry Parameters for A New Titanium‐Encapsulated Yb‐169 Source by Monte Carlo Calculations

Abstract

Purpose:To determine the AAPM TG‐43 brachytherapy dosimetry parameters of a new titanium‐encapsulated Yb‐169 source designed to maximize the dose enhancement during gold nanoparticle‐aided radiation therapy (GNRT).Methods:An existing Monte Carlo (MC) model of the titanium‐encapsulated Yb‐169 source, which was described in the current investigators’ published MC optimization study, was modified based on the source manufacturer's detailed specifications, resulting in an accurate model of the titanium‐encapsulated Yb‐169 source that was actually manufactured. MC calculations were then performed using the MCNP5 code system and the modified source model, in order to obtain a complete set of the AAPM TG‐43 parameters for the new Yb‐169 source.Results:The MC‐calculated dose rate constant for the new titanium‐encapsulated Yb‐169 source was 1.05 ± 0.03 cGy per hr U, indicating about 10% decrease from the values reported for the conventional stainless steel‐encapsulated Yb‐169 sources. The source anisotropy and radial dose function for the new source were found similar to those reported for the conventional Yb‐169 sources.Conclusion:In this study, the AAPM TG‐43 brachytherapy dosimetry parameters of a new titanium‐encapsulated Yb‐169 source were determined by MC calculations. The current results suggested that the use of titanium, instead of stainless steel, to encapsulate the Yb‐169 core would not lead to any major change in the dosimetric characteristics of the Yb‐169 source, while it would allow more low energy photons being transmitted through the source filter thereby leading to an increased dose enhancement during GNRT. Supported by DOD/PCRP grant W81XWH‐12‐1‐0198This investigation was supported by DOD/PCRP grant W81XWH‐12‐1‐ 0198.