Abstract
The term pure red cell aplasia (PRCA) indicates a heterogeneous group of congenital or acquired blood disorders characterized by anemia, reticulocytopenia, and paucity of erythroid precursors in an otherwise normally cellular bone marrow. Some forms of PRCA appear to have an immune-mediated pathogenesis; both humoral inhibitors and T-cell mediated inhibition of erythropoiesis have been described. We describe the case of a child with immune-mediated PRCA who was successfully treated by high intravenous doses of gamma-globulin.
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