Successful treatment of interstitial pregnancy with high level of β-human chorionic gonadotropin using methotrexate injection

Shen J,Onoue M,Hashimoto N,Takayama T,Ozaki K,Hatta K,Funato T,Yano Y,Yoshimi K,Saeki N,Hosoi A

doi:10.15761/jpr.1000137

Abstract

Successful treatment of interstitial pregnancy with high level of β-human chorionic gonadotropin using methotrexate injection

Highlights

Interstitial pregnancy is a rare kind of ectopic pregnancy
We report a case of successful treatment of interstitial pregnancy with a high level of β-human chorionic gonadotropin (β-hCG) using systemic methotrexate (MTX) injection
Interstitial pregnancy is a rare but dangerous form of ectopic pregnancy whose incidence has increased due to the increased use of assisted reproductive technology procedures

Summary

Introduction

Interstitial pregnancy is a rare kind of ectopic pregnancy. It is defined as a pregnancy in which the product of conception is implanted in the intramural portion of the fallopian tube [1]. Ectopic pregnancies account for approximately 2% of all recognized pregnancies, while interstitial pregnancies account for less than 2–4% of all ectopic pregnancies [2]. The overall mortality rate in ectopic pregnancies has decreased, the maternal mortality rate in interstitial pregnancies remains in the range 2–2.5%. We report a case of successful treatment of interstitial pregnancy with a high level of β-human chorionic gonadotropin (β-hCG) using systemic methotrexate (MTX) injection

Case presentation

Findings

Discussion