Hormone-replacement-therapy-and-successful-pregnancy-in-a-patient-with-premature-ovarian-failure

Eljabu H,Elfortia I,Andisha A

doi:10.15761/jpr.1000160

Abstract

hormone-replacement-therapy-and-successful-pregnancy-in-a-patient-with-premature-ovarian-failure

Highlights

Premature Ovarian Failure (POF) is not a rare condition with an incidence estimated at 1 % among patients less than 40 years old [1]
The reported case concerns a young woman with Premature Ovarian Insufficiency (POI) of an autoimmune cause (Hypothyroidism) who showed a resumption of her ovarian function and achieved a spontaneous pregnancy after a period of six months of Hormone Replacement Therapy (HRT)
POI does not indicate a permanent cessation of ovarian function as 20 % of those women affected spontaneously ovulated while some need medical therapy [8]

Summary

Introduction

Premature Ovarian Failure (POF) is not a rare condition with an incidence estimated at 1 % among patients less than 40 years old [1]. The reported case concerns a young woman with POI of an autoimmune cause (Hypothyroidism) who showed a resumption of her ovarian function and achieved a spontaneous pregnancy after a period of six months of HRT. The patient was a 33-year-old woman who had primary infertility over five years with a female factor (normal semen analysis and absence of organic causes) She had her menarche at 12 years old with regular cycles, lasting 3 to 5 days, with a normal Body Mass Index (BMI) of 26. Her personal and family history was unreliable apart from a positive history of Hypothyroidism with treatment (thyroxin) and no family history of POI. At the 38th week of gestation, an elective cesarean section was performed and a healthy child was born

Discussion

Findings

Conclusion