Abstract
Pseudohypoparathyroidism (PHP) refers to broad spectrum of genetic diseases characterized by peripheral resistance to Parathormone (PTH). This condition leads to hypocalcaemia, hyperphosphatemia and elevated PTH concentrations. There is scant literature on PHP in pregnancy with 9 cases published. The treatment of the disease in pregnant women is challenging and the main target is to avoid hyper/hypocalcemia to prevent maternal adverse effects and to protect fetal parathyroid glands development. We report a rare case of PHP type 1b in pregnant woman treated with a tailored therapy.
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