Abstract
The aim of this paper is to share the initial results of LLDN in high-volume university centre that is performing laparoscopic nephrectomies for other indications. During 2017, four LLDNs were performed. The transperitoneal approach was used in all cases and the kidney was removed using a suprapubic incision. All donors and recipients were prospectively analysed within six-month follow-up. The patients' clinical, laboratory, and operation-related data were collected from direct interviews with them and from medical records. All patients signed written informed consent. One male and three females donated their left kidneys by using the LLDN technique. The mean age was 58 ± 9 years; two of them with a history of previous cholecystectomy. All donated kidneys had a single renal artery and renal vein. Pre-operative average eGFR was 94.2 ± 7.1 ml/min/1.73 m2, immediately after LLDN 57.5 ± 10.3 ml/min/1.73 m2, after one month 56.0 ± 9.1 ml/min/1.73 m2. There were no intraoperative complications; surgery duration was 223.75 ± 21.74 min, the cold ischemia time was 77.5 ± 28.77 min, and the warm ischemia time 6.37 ± 3.14 min. There was one postoperative donor complication, one case of acute kidney injury, and one case of prolonged postoperative abdominal pain. The only recipient complication was one case of acute kidney rejection; there were no cases of delayed graft function. Our initial experience confirms that LLDN is an approach that is easy to learn, especially in a high-volume university hospital with expertise in performing laparoscopic nephrectomies for other indications.
Highlights
End-stage renal disease (ESRD) is prevalent in 0.1% of population worldwide [1]
We report the primary results of four successful LLDNs performed at Vilnius University Hospital Santaros Klinikos
Compared to other European countries it is the lowest rate of living donor kidney transplantations along with Poland, Belarus, Bulgaria, Romania, Croatia, Bosnia and Hercegovina, and Ukraine [25]
Summary
End-stage renal disease (ESRD) is prevalent in 0.1% of population worldwide [1]. There is no perfect renal replacement therapy method for ESRD, but a kidney transplant should be a treatment of choice for these patients. Since 2005 only 99 living kidney transplants have been accomplished in Lithuania, 95 of them by using open donor nephrectomy (ODN) approach. The introduction of AB0 incompatible kidney transplant in our centre had only temporary beneficial effect in increasing the numbers of living kidney donations. We observed that the choice of the surgical technique might play an important role for possible kidney donors before making the final decision [2]. The aim of this paper is to share the initial results of LLDN in high-volume university centre that is performing laparoscopic nephrectomies for other indications
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