Abstract
Prognosis in neonatal endocarditis depends on early diagnosis and the status of the patient at the time of diagnosis, and effective treatment with appropriate antibiotics. The current case report describes a case of successful conservative treatment of endocarditis in a 26 day old male neonate, previously inadequately treated for septicaemia in another hospital. DOI: http://dx.doi.org/10.3126/jnps.v33i1.7045 J Nepal Paediatr Soc. 2013;33(1):70-73
Highlights
With the advent of neonatal intensive care and use of long IV-lines, especially for parenteral nutrition, more and more cases of infective endocarditis (IE) are diagnosed
This prevalence of infective endocarditis (IE) in infants with normal hearts is partly related to the increased frequency of sepsis in these infants
When IE develops in newborn infants, it is associated with a very high mortality rate; the diagnosis is often made at post-mortem examination[2,3,4]
Summary
With the advent of neonatal intensive care and use of long IV-lines, especially for parenteral nutrition, more and more cases of IE are diagnosed. Neonates with IE usually do not have underlying structural heart anomalies. All neonates with persistent or recurrent sepsis in an intensive care setting should be worked up for IE. A high index of suspicion, early diagnosis and treatment may affect the outcome favourably. This case is appropriate for reporting as this is a rare successful management of neonatal endocarditis on conservative therapy as the mortality in most cases is very high
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