Abstract
IMP synthase is a bifunctional enzyme containing the activities, 5-aminoimidazole-4-carboxamide ribotide (AICAR) transformylase (EC 2.1.2.3) and IMP cyclohydrolase (EC 3.5.4.10) and catalyses the ninth and tenth reactions of the pathway for de novo biosynthesis of purine nucleotides.
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