Abstract
It is now considered that the major component of mucus, MUC5AC, is mainly produced by goblet cells but not submucosal glands, and the role of the submucosal glands in the production of MUC5AC is unclear. The aim of this study was to clarify whether human submucosal glands produce MUC5AC. Immunohistochemical analysis with MUC5AC antibody of lower airways resected from six lung cancer patients and three patients with acute myocardial infarction was performed. The submucosal glands contained both MUC5AC-positive cells and non-positive cells. These data suggest that MUC5AC protein is produced in both goblet cells and in airway submucosal glands.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
