Sub-foveal choroidal thickness in acute central serous chorioretinopathy and its correlation with central macular thickness

Abstract

Purpose The aim of the study was to measure subfoveal choroidal thickness (SFCT) in eyes with central serous chorioretinopathy (CSCR), to compare it with that of contralateral clinically unaffected eyes and with that of other healthy persons, and to study its correlation with central macular thickness (CMT). Patients and methods Fifty-four eyes of 36 (23 male and 13 female patients) patients were included in this study under three groups: 18 eyes with recent unilateral CSCR, 18 free fellow eyes of patients with unilateral CSCR, and 18 healthy eyes of age-matched normal controls. Spectral-domain optical coherence tomography was performed to measure SFCT in all eyes and CMT in eyes with CSCR. Results The mean patient age was 37.4 years, whereas that of normal controls was 38.0 years. The mean SFCT was 332.0 μm in eyes with CSCR, 247.25 μm in the unaffected fellow eyes, and 248.74 μm in normal control eyes. SFCT in eyes with CSCR was significantly greater than that in each of the unaffected fellow eyes and normal control eyes, whereas there was no significant difference between fellow eyes and control eyes. The mean CMT in eyes with CSCR was 477.62 μm with a significant positive correlation with SFCT. Conclusion Subfoveal choroid in eyes with acute unilateral CSCR was significantly thicker than that in contralateral clinically unaffected eyes and that in healthy eyes of age-matched normal controls, whereas it was not significantly different between contralateral unaffected eyes and normal eyes. CMT was positively correlated with SFCT in eyes with CSCR.