Abstract
Subcutaneous Panniculitis-like T-cell lymphoma (SPTCL) is characterized by malignant lymphoid cell infiltration within the lobules of panniculitis. Diagnosis of SPTCL requires distinguish from primary cutaneous c/d T-cell lymphoma, peripheral T-cell lymphoma, and lupus panniculitis. We reported 4 cases with the diagnosis of SPTCL. Five patients were admitted to the hospital with skin lesions (erythema nodosum, skin thickening, skin ulcers) accompanied by persistent fever. Skin biopsies of them have infiltrative images of septal adipose tissue inflammation, immunohistochemical staining were positive for CD3, CD4, CD8, high Ki index. SPTCL is mainly based on biopsy. If SPTCL is diagnosed early, the prognosis is good.
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