Abstract
Subclinical hyperthyroidism is characterized by low circulating TSH concentrations, together with normal concentrations of free T4 and free T3. The clinical significance of low but detectable TSH values is likely to be different from undetectable TSH values. The question remains as to whether endogenous and exogenous (iatrogenic) causes of low serum TSH have the same clinical significance. Subclinical hypothyroidism is characterized by high serum TSH concentrations, together with normal free T4 values.
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