Abstract
Two ‘alkaline earth silicate’ wools—a calcium magnesium silicate and a calcium magnesiumzirconium silicate—were examined in a subchronic ‘90-day’ rat inhalation assay. A prepar-ation of a high-purity refractory ceramic fibre (RCF), a non-fibrous particulate (NFP) with thesame, aluminosilicate chemical composition and a sample of long-fibred amosite were alsoexamined. The assay was similar to that proposed by the European Union but was undertakenbefore that protocol was finalized. Exposure was to a single fibre concentration only (150 fibres>20
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