Subacute sclerosing panencephalitis (SSPE) without electroencephalographic evidence throughout the illness: An unusual finding, challenging the diagnosis

Abstract

SSPE is a chronic progressive encephalitis due to persistent measles viral infection. Clinical features, neuroimaging, EEG, CSF and serum measles antibody levels assist in the diagnosis. We report a case of SSPE confirmed by CSF measles antibodies and MRI abnormalities but without myoclonus or characteristic EEG changes.