Abstract
Subacute sclerosing panencephalitis (SSPE) is a known rare cause of progressive myoclonic encephalitis of childhood and young adults due to a persistent measles virus infection. It is usually characterised by myoclonic jerks, cognitive decline , typical EEG findings that clinches its diagnosis and further supported by a high CSF and serum measles antibody titre.
Highlights
sclerosing panencephalitis (SSPE) is an inflammatory condition of the brain due a persistent mutant measles virus infection [1]
Subacute sclerosing panencephalitis (SSPE) is a known rare cause of progressive myoclonic encephalitis of childhood and young adults due to a persistent measles virus infection. It is usually characterised by myoclonic jerks, cognitive decline, typical EEG findings that clinches its diagnosis and further supported by a high CSF and serum measles antibody titre
SSPE is an inflammatory condition of the brain due a persistent mutant measles virus infection [1]
Summary
SSPE is an inflammatory condition of the brain due a persistent mutant measles virus infection [1]. Subacute sclerosing panencephalitis (SSPE) is a known rare cause of progressive myoclonic encephalitis of childhood and young adults due to a persistent measles virus infection. It is usually characterised by myoclonic jerks, cognitive decline , typical EEG findings that clinches its diagnosis and further supported by a high CSF and serum measles antibody titre. Patients with SSPE are usually infected with measles virus in the early age [3]. The diagnosis of SSPE is made when three out of five criteria given by Dyken are fulfilled which involved clinical, EEG, CSF analysis, anti-measles titre and brain biopsy [8,9,10].
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