Su1018 ENDOSCOPIC RETROGRADE APPENDICITIS THERAPY: CURRENT STATUS AND FUTURE DEVELOPEMENT IN CHINA

Abstract

Endoscopic retrograde appendicitis therapy (ERAT) is a minimally invasive method to treat acute appendicitis which was firstly proposed by Bingrong Liu in 2009 and became more accepted in general practice in China. This study aimed to introduce the application of ERAT in multicenter and prospect its future development. A multicenter retrospective analysis was recruited for the patients who underwent ERAT in China from November 2009 to September 2019. The primary data included: 1) number of hospitals performed ERAT in China; 2) patients with acute appendicitis treated by ERAT; 3) success rate of ERAT (defined as a successful intraoperative intubation, angiography, stenting); 4) effective rate of ERAT (defined as significant relief of postoperative abdominal pain, significantly decrease of temperature and white blood cells); 5) recurrence rate. Totally 3196 patients with appendicitis were treated by ERAT at 46 hospitals in China. Among them, we obtained 1576 patients information at 18 hospitals. The success rate was 93.6% (1475/1576) and the effective rate was 95.9% (1415/1475). During the follow-up (range from 1 week to 10 years), the recurrence rate was 6.2% (91/1475). As a safe and effective treatment for acute appendicitis, ERAT has been gradually promoted and popularized in the clinical in China. Multicenter prospective randomized controlled studies are needed before it recommend as first line choice. The diagnosis and treatment of acute appendicitis will be changed by ERAT in the near future.