Abstract
Polymorphs is present in many crystalline drug, different crystal type tend to produce different effects. Drug quality and curative effect of the important quality index is drug heteromorphic stability .The change of drug heteromorphic will change the nature, quality, efficacy of the drug. Generally speaking, the greater the crystal particle size, heating melting needs more energy, the more stable. The crystal type which has high melting point, the chemistry stability is good, but the solubility and digestion rate is low. HMP has different polycrystalline forms, at present reports in the literature there are two kinds of crystal type, form Ⅰ and form Ⅱ. The form Ⅰ is more stable than form Ⅱ, and has higher melting point. This article research the relationship between HMP polymorphism and melting point based with the drug melting point meter and DSC.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
