Abstract
The aim of this study was to investigate the role of Chlamydia trachomatis as a risk factor in ectopic pregnancy in Iraqi women. The study involves two groups, the first group included 24 women diagnosed as ectopic pregnancy, while the second group included 24 women as control group diagnosed as normal pregnancy. Both groups were admitted to Al-Elweya Teaching Hospital, Baghdad from November 2009 to July 2010. Serum antichlamydial antibodies were investigated in both studied groups using enzyme_linked immunosorbent assay (ELISA). Results revealed a significant(p<0.05) percentage of IgG antichlamydial antibodies in women detected as ectopic pregnant, as compared with control normal pregnant (45 vs. 8.3%). On the other hand, ectopic pregnant women exhibited low (p<0.05)IgM antichlamydial antibodies 4% as compared with control group. In conclusion all women with seropositive to Chlamydia trachomatis antibodies had pelvic inflammatory disease (PID).
Highlights
The aim of this study was to investigate the role of Chlamydia trachomatis as a risk factor in ectopic pregnancy in Iraqi women
(PID)انخٓبة يُطقت انحٕض Introduction Ectopic pregnancy (EP) is defined as a pregnancy in which the implantation of the embryo occurs in the early first weeks outside the uterine cavity, most frequently in one of the two fallopian tubes or, more rarely, in the abdominal cavity [1] while in normal pregnant cases the sperm fertilizes the ovum in fallopian tube, the zygote passes to be implanted in the uterus to grow [1, 2]
The major causes of EP are pelvic inflammatory disease (PID) which is caused by bacteria such as Chlamydia trachomatis and gonorrhea
Summary
These results are in agreement with other studies that reported the prevalence of IgM in women with EP was 3% [16]. Sixteen women in group I (66%) reported PID history compared with 4 (15%) in group II. Women with PID have five times greater risk for EP [18]. Result from previous studies lend support that smoking is a risk factor for the occurrence of tubal pregnancy [19]. This may be due to the nicotine in cigarettes. Nicotine can cause temporary blockage of the tube so the embryo cant pass through. [20]
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