Study the possibility of the effect of fluoxetine on the process of implantation of the blastocyst in the uterus of pregnant albino rats?

Abstract

The current study dealt with knowing the effect of fluoxetine on the process of implantation of the blastocyst in the uterus of pregnant rats, which occurs in the rat on the sixth day of pregnancy because the implantation of the blastocyst is a very critical period of pregnancy. 26 females and male rats were used. Female rats were divided into two groups, the control group, and included 4 rats injected with the physiological solution inside the peritoneal cavity from day zero of pregnancy. The treatment group of 12 females was divided into two groups, the first included 4 females who were injected from day 0 of pregnancy with fluoxetine 20 mg/kg of body weight, and the second also included 4 females who were injected from day 0 of pregnancy with 40 mg/kg of body weight, and the third also included 4 females. From day 0 of pregnancy, she was injected with fluoxetine 60 mg/kg body weight. The histological technique was applied to uterine sections on the 7th day of pregnancy, and samples were stained with hematoxylin-eosin stain.