Abstract
Background: For a long time, researchers have extensively studied the health advantages of natural products derived from plants. Objective: The main goal of this study is to investigate the effects of palm heart extract (PHE) on the lipid profile and various parameters of the heart, liver, and reproductive system in male rabbits. Methods: The male rabbits were divided into four groups by chance; one group was given a standard diet for comparison, while the other three received a PHE supplement. The control group did not get any treatment while three groups were given medium to high doses of PHE daily for 8 weeks. Troponin and lipid profile levels were assessed for health indicators, while liver enzyme levels (ALT, AST, ALP) and total bilirubin were analyzed to evaluate liver function. Furthermore, hormone levels such as testosterone, LH (luteinizing hormone), and FSH (follicle stimulating hormone) were also observed during the entire study period. Outcomes: Lipid profile parameters, including cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL), and high density lipoprotein cholesterol (HDL), were assessed before and after the intervention period. Results: The results indicated a reduction in TC and LDL levels in the treatment group compared to the control group was statistically significant (p < 0.05). Nonetheless, there were no changes observed in the levels of TG and HDL in both groups, with a p-value greater than 0.05. These results indicate that heart palm water extract might have the ability to lower lipid levels, especially in decreasing total cholesterol and LDL levels. Testosterone levels showed a small drop in the high dose group when compared to the control group, although there was no statistical significance (p > 0.05). LH levels did not significantly decrease in the medium dose group compared to the control group (p < 0.05). There were no notable variations in FSH levels among the groups (p < 0.05). In conclusion, male rabbits showed reduced troponin levels in a dose-dependent manner, indicating potential cardioprotective effects of HDP extract. The administration of HDP extract did not have any impact on liver function. Although reproductive hormone levels varied, additional research is required to understand the effects of heart palm extract on male reproductive health.
Published Version
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