Abstract
Background: Taurine is sulfur containing semi-essential amino acid that has important roles in many biological processes, but; its effects on glucose homeostasis, weight; growth and bone mineralization were not well defined in human. Objectives: evaluation the effects of oral taurine used for 3 months on bone mineralization biomarker; glycemic control and body weight in type II diabetic patients. Methods: interventional double-blind placebo-controlled study in which 80 patients with type2 diabetes mellitus (age range 45e55) assigned in either control (n ¼ 40) or study (n ¼ 40) group. The last group received 1000 mg capsule of taurine once a -d for three months. Parameters measured were serum calcium, 25(OH) vitamin D and osteocalcin, NTX-1; HbA1C% and Fasting blood glucose before and after 3 months. Results: Taurine led to significant (p < 0.05) rise in osteocalcin and significant lowering in Body weight and BMI and there were no significant changes in Serum Calcium; NTX-1; Vitamin D; HbA1C% and fasting blood glucose; all as compared with control values. Conclusion: 3 months of oral Taurine used in type II diabetic patients may modulate bone mineralization represented by elevation of osteocalcin; and reduction of body weight, but has no significant effect on glycemic control and did not reduce HbA1C%
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
