Study on the therapeutic effect of non-invasive ventilator on hypoxemia after laparoscopic operation for gastroesophageal reflux disease

Abstract

Objective To investigate the effect of non-invasive ventilator on hypoxemia after laparoscopic operation for gastroesophageal reflux disease (GERD). Methods from October 2015 to October 2018, 120 patients with gastroesophageal reflux disease after laparoscopic operation were randomly divided into two groups: the experimental group (n=60) and the control group (n=60). The patients in the experimental group were treated with non-invasive ventilator. The therapeutic effects, hemodynamic parameters, respiratory parameters and adverse reactions were compared between the two groups before and after treatment. Results the total effective rate in the trial group (96.7%) was significantly higher than that in the control group (78.3%) (P＜0.05). After treatment, the mean arterial pressure, heart rate, respiratory rate, arterial blood PaO2, PaCO2 and pH in the experimental group were significantly higher than those in the control group (P＜0. 05), and there were no adverse reactions in both groups. Conclusion the adjuvant treatment of non-invasive ventilator can significantly improve the symptoms of hypoxemia in patients with gastroesophageal reflux disease after laparoscopic operation. Key words: gastroesophageal reflux disease; Laparoscopic surgery; Non-invasive ventilator; hypoxemia; Therapeutic effect