Abstract
To study the preventive and therapeutic effects of Allium Macrostemon Powder (AP) on experimental ulcerative colitis and its antioxidant and anti-inflammatory effects in vitro. Sodium dextran sulfate (DSS) was used to establish the model of ulcerative colitis in mice. Lipopolysaccharide (LPS) was used to induce cell inflammation. The scavenging capacity of AP on ABTS and DPPH free radicals was measured in vitro. The results showed that the drug had no significant effect on colitis, but cell experiments in vitro showed that it had obvious anti-inflammatory effect, and had good scavenging ability on ABTS and DPPH free radicals. AP has anti-inflammatory and antioxidant effects.
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