Study on the efficacy of tranexamic acid among pregnant women in reducing blood loss in lower segment cesarean section

Abstract

Introduction: With reference to WHO, about 30% of maternal deaths were due to postpartum haemorrhage (PPH) which is a major complication in cesarean delivery. It has become imperative to reduce the amount of blood loss during and after LSCS-lower segment cesarean section in order to decrease the rate of maternal morbidity and mortality that occur as a result of bleeding. Prior administration of Tranexamic acid has great potential to prevent excessive loss of blood. Hence, this study was an attempt to assess the effectiveness of Tranexamic acid in reducing blood loss in LSCS. Materials & Methods: This is a prospective study carried out on 50 human subjects who were classified into two separate groups (Groups A and B respectively). Group A subjects (n=25) were considered the control group who were administered with distilled water before the surgery and group B subjects (n=25) were considered to be the test group who were administered with 1g of Tranexamic acid. During the surgery, bleeding occurred and the blood was collected and measured between the periods of placental delivery until the end of lower segment caesarean section and for a period of two hours postpartum.