Abstract
This paper explores the relationship between magnetic resonance diffusion-weighted imaging of nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS), as well as the study of diffusion-weighted imaging, spectral imaging, and low density of nonalcoholic fatty liver correlation between serum concentration of lipoprotein cholesterol (LDL-C). This collection is from February 2018 to May 2018 in hospital as 39 cases of nonalcoholic fatty liver patients in the observation group and 39 patients in the control group with the same period of physical examination. All patients underwent magnetic resonance spectroscopy imaging, magnetic resonance diffusion-weighted imaging examination, and serum LDL-C test, compared the results of the two groups, and analysed the correlation between magnetic resonance spectroscopy imaging and magnetic resonance diffusion-weighted imaging examination results and LDL-C. The results showed that the prevalence of NAFLD was 12.33%, and the prevalence of NAFLD and MS was 3.47%. Magnetic resonance spectroscopy observation parameter group and the control group had statistically significant difference when compared ( P < 0.05). Difference was statistically significant ( P < 0.01). In conclusion, nonalcoholic fatty liver DWI and MR spectroscopy is closely related to LDL-C targets, quantitatively and noninvasively reflects the body’s fat metabolism, and can provide more extensive clinical diagnosis of nonalcoholic fatty liver. NAFLD is closely related to MS. The mutual aggravation and mutual promotion in the pathogenesis of the two should arouse enough attention and comprehensive prevention and treatment.
Highlights
Nonalcoholic fatty liver disease (NAFLD) refers to a group of liver diseases caused by the accumulation of fat, including liver steatosis, steatohepatitis, and combined inflammatory changes, fibrosis, and necrosis, with chronic inflammatory changes, necrosis, liver cirrhosis, and other diseases that progress to the end stage
body mass index (BMI), SBP, DBP, TG, TC, LDL-C, FPG, ALT, AST, GGT, and UA were higher than those of group (P < 0.01), and low HDL-C ratio has a simple set of statistical significance (P < 0.01). ere was no significant difference in TC between the normal group and the simple group (P > 0.05) [6]
WHO’s definition of metabolic syndrome (MS) includes Insulin resistance (IR), and it is a necessary condition for the diagnosis of MS. e results of this study showed that BMI, SBP, DBP, TG, TC, LDL-C, FPG and other MS-related indicators in the NAFLD group were higher than those of the normal group (P < 0.01), and HDL-C was lower than the normal group (P < 0.01); and with the increase in MS diagnosis items, the prevalence of NAFLD increases, indicating that the prevalence of NAFLD increases with the increase in metabolic disorders [7]
Summary
Nonalcoholic fatty liver disease (NAFLD) refers to a group of liver diseases caused by the accumulation of fat, including liver steatosis, steatohepatitis, and combined inflammatory changes, fibrosis, and necrosis, with chronic inflammatory changes, necrosis, liver cirrhosis, and other diseases that progress to the end stage. NAFLD is a clinical disease with hepatocellular steatosis and fat accumulation as pathological features and no history of excessive drinking. Magnetic resonance spectroscopy imaging technology is the only noninvasive imaging technique that can reflect the pathological and physiological changes of living tissues from the perspective of molecular metabolism. Diffusion weighted imaging (DWI) is the only viable tissue that can detect the thermal motion of water molecules in non-invasive magnetic resonance imaging technology. In order to study the Scientific Programming relationship between LDL-C in patients with nonalcoholic fatty liver MRS and DWI and low-density lipoprotein cholesterol, the relevant case data analysis is selected and researched. In order to study the Scientific Programming relationship between LDL-C in patients with nonalcoholic fatty liver MRS and DWI and low-density lipoprotein cholesterol, the relevant case data analysis is selected and researched. e report is as follows [1]
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