Abstract
Objective To investigate the survival status of patients with thymoma, and provide scientific basis for improving the living conditions of thymoma. Methods This study retrospectively analyzed the clinical data of 62 cases of thymoma by surgical treatment from January 2005 to December 2010, including sex ratio, age distribution, whether associated with smoking, whether accompanied by drinking, surgery, WHO histological classification, tumor diameter, whether complicated with myasthenia gravis, Latter/Bematz (L/B) standard histological classification, Masaoka stage, invasion degree, through kaplan-meier analysis to identify the related factors, through COX multi factor analysis independent factors determine the survival status of thymoma. Results Five years survival rate of patients with thymoma was 51.6% (32/62), the single factor analysis showed that WHO surgery, histological classification, Masaoka stage was the 5 year survival rate of thymoma associated factors; 10 years survival rate of thymoma patients was 41.9% (26/62), gender, age distribution, operation mode, WHO standard histological classification, Masaoka stage was the correlation factors of 10 years survival rate of patients with thymoma. Surgical approach and Masaoka staging were independent risk factors of the 5 years survival rate of patients with thymoma; age, surgery and Masaoka stage were independent factors affecting the 10 years survival rate of patients with thymoma. Conclusions The operation mode and Masaoka stage were independent factors affecting the survival rate of 5 years of thymoma patient; age, operation mode and Masaoka staging were independent factors affecting the survival rate of 10 years of thymoma patients, in order to further prolong the survival time of patients. For patients over 50 years old, patients who cannot complete resection of the tumor and Masaoka stage of stage Ⅲ and Ⅳ, we should be given more attention and related measures. Key words: Thymoma; Living condition; Influencing factors
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