Abstract
Objective To study protective effect of Wu-He Dipsacus asper(WHDA) injection on the radiation damaged mice. Methods One hundred and twenty Kunming female mice were divided into normal control group, model control group, Wu-He Dipsacus asper treatment group to observe the 30-day survival rate;measured peripheral blood 6 hours, 3 days, 6 days and 9 days after irradiation, respectively; thymus, spleen and liver weight were detected; superoxide dismutase (SOD), glutathione (GSH), malonyldialdehyde (MDA) in liver and peripheral blood were also detected. Results WHDA can improve the survival rate of mice after radiation, and take a significant influence on white blood cells and platelets, but no obvious effect on the weight of thymus, spleen and liver. In addition, WHDA can improve SOD activity, increased GSH content and decrease MDA content significantly in this study. Conclusion WHDA has obvious protective effect in mice with radiation injury. Key words: Radiation injuries; Radiation protection; Wu-He Dipsacus asper
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.