Study on Molecularly Imprinted Electrochemical Sensor for Bisphenol a Based on Nb2O5/GO/NiCo

Abstract

In this paper, a molecularly imprinted electrochemical sensor (miecs) for rapid and sensitive detection of bisphenol A (BPA) based on double-layer Nb2O5 / rGO loaded hollow nickel cobalt nanorod modified glassy carbon electrode (GCE) is proposed for the first time. The NiCo bimetallic nanorods (NiCo) were modified by double-layer Nb2O5 / rGO loaded hollow Ni Co nanorods, which expanded the active region and electronic transmission ability of the sensor signal. Molecular imprinted polymer (MIP) could further enhance the electrical signal. Then, MIP was polymerized by cyclic voltammetry (CV) with o-phenylenediamine as monomer and bisphenol A (BPS) as template, and BPA was detected by differential pulse voltammetry (DPV). At the same time, the factors affecting the response of the sensor were optimized, and the experimental conditions such as the molar ratio of monomer to template and pH were optimized. The results showed that miecs had good sensitivity, selectivity, reproducibility and stability to BPA when pH = 7.0 and the molar ratio of monomer to template was 4:1. The recoveries of actual samples (95.9% - 100.9%) and reasonable relative standard deviations (RSD) (3.2% - 4.8%) indicate that the sensor has strong practical potential, and has broad application prospects in the rapid determination of bisphenol A in samples such as metal cans and baby bottles.