Abstract
Objective: To study the effect of Astragalus (As) on left ventricular collagen remodeling after myocardial infarction in rats.Methods: Myocardial collagen (MC) and ratio of myocardial collagen type I and M in rat models of myocardial infarction treated with Astragalus injection were determined and compared with those in sham operated rats and in captopril(CAP) treated rats.Results: MC and ratio of MC I /IE of non-in-farcted region in the myocardial infarction rats was higher than that in the sham group. Both AS and CAP could restrain the ascending trend of these parameters.Conclusion: Astragalus is effective in lowering the elevation of MC after infarction and changing the MC I /H ratio, therefore, is beneficial to improve the systolic and diastolic function of left ventricle after acute myocardial infarction.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
