Abstract
Background: The species belonging to the genus Leea, Leeaceae are reported to have anti-inflammatory, antioxidant, analgesic, antibacterial effects, and have been used to treat osteoarthritis pain, rheumatism, digestive and cancer diseases. The project aims to study botanical characteristics and Acetylcholinesterase inhibitory activity of two species of genus Leea. Materials and method: Two species Leea rubra Blume ex Spreng. and Leea curtisii King., Leeaceae were identified the powder characteristics, microsurgical characteristics by double dyeing method, determined Acetylcholinesterase inhibitory activity by the method of Ellman. Results: Identified characteristics of microsurgery and powder of 2 studied species; total extracts and fractional extracts of 2 studied species shown the average Acetylcholinesterase inhibitory activities with the IC50 values in the range of 42.44 to 97.96 µg/ml. Conclusion: The project contributed to standardize microbiological characteristics and determined Acetylcholinesterase inhibitory activity of two species belonging to the genus Leea. Key words: Acetylcholinesterase, Leea rubra, Leea curtisii, microsurgery, powder characteristics
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