Study of weight loss induction activity of Camellia sinensis, Cynara scolymus, and Coffea robusta

Abstract

This research reports on the effectiveness of herbal infusions (Camellia sinensis, Cynara scolymus, and Coffea robusta) in promoting weight loss in mice. Amongst the infusions, Coffea robusta showed significant weight loss induction in a high-fat diet mouse model (up to 28.11% weight loss). The study also evaluated the total polyphenol content and antioxidant activity of the infusions. Camellia sinensis infusions exhibited the highest total polyphenol values (69.53 ± 0.5 mgGAE/g). Furthermore, this infusion demonstrated impressive antioxidant activity with an IC50 value of 24.45 ± 0.98 μg/mL.