Abstract
Introduction: Diabetes is defined as a disturbance in intermediary metabolism manifesting aschronic sustained hyperglycemia, primarily due to either an absolute or a relative lack of insulin.Many epidemiological studies have demonstrated an inverse relationship between vitamin D levelsand diabetes mellitus. However, there is a paucity of literature regarding the levels of vitamin D intype 2 diabetes, which is common in our community. This study was taken up to shed more light onthis issue. Material and methods: This was a cross-sectional study conducted at NRI Institute ofMedical Sciences, Sangivalasa, Visakhapatnam district. Cases of Type 2 Diabetes Mellitus attendingto the outpatient department, diagnosed as per the ADA criteria of 2011, between the ages of 31and 75 years constituted the material for the present study. Results and conclusion: Vitamin Dlevels were found to be significantly lower in the study group (19.91±7.0 ng/ml) as compared to thecontrol group (32.22±4.0 ng/ml).
Highlights
Diabetes is defined as a disturbance in intermediary metabolism manifesting as chronic sustained hyperglycemia, primarily due to either an absolute or a relative lack of insulin
This study suggested an inverse relationship between HbA1c levels and vitamin D, with HbA1c higher in the subjects with vitamin D deficiency (< 20 ng/ml) (8.11±1.11% vs 7.33±1.32%, p = 0.046)
This study suggests that hypovitaminosis D is more prevalent among diabetic as compared to the nondiabetic population
Summary
Diabetes is defined as a disturbance in intermediary metabolism manifesting as chronic sustained hyperglycemia, primarily due to either an absolute or a relative lack of insulin. There is a paucity of literature regarding the levels of vitamin D in type 2 diabetes, which is common in our community. Cases of Type 2 Diabetes Mellitus attending to the outpatient department, diagnosed as per the ADA criteria of 2011, between the ages of 31 and 75 years constituted the material for the present study. Results and conclusion: Vitamin D levels were found to be significantly lower in the study group (19.91±7.0 ng/ml) as compared to the control group (32.22±4.0 ng/ml). Many epidemiological studies have demonstrated an inverse relationship between vitamin D levels and diabetes mellitus [2,3]
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