Precipitating Factors of Psoriasis in North Indian Population

Dr Kamlesh Kumar Bhaskar, ,Dr Kavita Chawla,Professor Of Physiology, Mlnmc, Prayagraj, Uttar Pradesh, India ,Dr Beenu Beenu,Professor Of Biochemistry, Mlnmc, Prayagraj, Uttar Pradesh, India ,Assistant Professor Of Biochemistry, Mlnmc, Prayagraj, Uttar Pradesh, India ,Dr Rakesh Kumar Shukla,Assistant Professor Of Anatomy, Asmc, Mirzapur, Uttar Pradesh, India ,Dr Archana Mishra

doi:10.17511/ijmrr.2021.i05.01

Dr Kamlesh Kumar Bhaskar, + Show 8 more

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https://doi.org/10.17511/ijmrr.2021.i05.01

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Abstract

Aim: This study aims to study precipitating factors of psoriasis in the north Indian population.Material & Method:Two hundred twenty-eight psoriasis patients regardless of age, sex, religion,occupation, attending the skin, and V.D. outpatients Department, B.R.D. Medical College, Gorakhpurfor were taken because of the subject of this study. The bulk of patients belonged to the Eastern U.P.and adjoining areas of Bihar and Nepal. The clinical criteria for diagnosis of psoriasis were thepresence of Erythematous and papulosquamous lesions with loosely adherent silvery-white scales.The auspitz's sign was demonstrated all told the cases. The detailed clinical history and examinationwere recorded. Each patient was categorized into mild to severe psoriasis. Result: The maximumpercentage of cases was aggravated by weather (winter), 55.26%, next to that was trauma 27.19%, and least after infections 4.35%. The summer and spring seasons showed an improved effecton the condition of psoriasis. Alcohol, smoking, and mental stress found no relation with psoriasis.In most cases, where the infection was associated with the disease, it had been aggravated only inchildren, and young adults and lesions were of guttate type. Pregnancy had no effect in 25.43% ofcases, while the disease was improved in 3.50% of patients and worsen in 4.35% of cases.Conclusion: Psoriasis is positively correlated with the winter season and negatively associated withSummer and Spring.

Highlights

Psoriasis is a common, genetically determined chronic, relapsing, inflammatory disorder of the skin characterized by red, scaly, sharply demarcated plaques that typically exhibit silvery-white scales.Psoriasis is one of the significant common chronic inflammatory diseases of the skin, affecting 2–3%of the population [1]
Aim: This study aims to study precipitating factors of psoriasis in the north Indian population
Patients with psoriasis were 4-5 times more likely to be colonized by Staphylococcus aureus (S. aureus) on the skin and 60% more likely to be colonized within the cavity compared with healthy controls [relative risk and 95% confidence interval (CI), skin: 5.54 (3.21-9.57); nares: 1.60 (1.112.32)] [13]

Summary

Introduction

Genetically determined chronic, relapsing, inflammatory disorder of the skin characterized by red, scaly, sharply demarcated plaques that typically exhibit silvery-white scales.Psoriasis is one of the significant common chronic inflammatory diseases of the skin, affecting 2–3%of the population [1]. Genetically determined chronic, relapsing, inflammatory disorder of the skin characterized by red, scaly, sharply demarcated plaques that typically exhibit silvery-white scales. Psoriasis is one of the significant common chronic inflammatory diseases of the skin, affecting 2–3%. There's no cure known for this disease, which is related to the extensive psychological and physical burden. This disease evolves overtime in an exceedingly complex interplay of heterogeneous genetic and environmental factors [2]. Psoriasis isn't only a skin problem but may include inflammation of the joints in psoriasis arthritis [3] and comorbidities like metabolic syndrome with increased insulin resistance, increased cardiovascular risk [4,5]. Almost all styles of trauma are known to be related to plaque psoriasis

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