Study of uric acid and microalbuminuria in preeclampsia and normal pregnant women

Abstract

Introduction and Aim: Pregnancy is complicated by the hypertension disease known as pre-eclampsia. The development of hypertension to a level of 140/90 mmHg or greater in the presence of proteinuria after the 20th week of gestation characterises this condition, a multisystem disorder with an unclear cause. Uric acid and microalbuminuria were assessed in preeclamptic women (PW) and normal pregnant women (NPW). Materials and Methods: For the present study 120 women (60 NPW and 60 PW) were selected from the hospital at Mullana, Ambala, Haryana. The level of uric acid and microalbuminuria were estimated in all subjects. Results: Preeclamptic women had microalbuminuria levels that were substantially (p<0.001) greater than those of normal pregnant women, and their uric acid levels were significantly (p<0.001) higher. Conclusion: Preeclampsia patients had significantly higher uric acid and microalbuminuria levels than normal pregnant women. We deduced from the study that uric acid and microalbuminuria can be helpful in diagnosing preeclampsia risk.