Abstract

One of the main factors determining the prognosis in patients with chronic heart failure (CHF) is endothelial dysfunction. The aim of the work was to determine the antithrombogenic and vasodilating activity of the vascular wall in patients with CHF. We examined 70 people, of whom 50 were the main group - patients with prior Q-myocardial infarction and 20 people - the comparison group. To determine the antithrombogenic properties of the vessel wall, we used a "cuff" test. The vasomotor function of the endothelium was studied in samples with reactive hyperemia (HR) and nitroglycerin (NTG). In patients with CHF, there is a decrease in the antithrombogenic and vasodilating activity of the vascular wall. In patients with IV FC CHF, with a long duration of symptoms of CHF, FW<.

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