Study of the Effect of Oil Extract of Dill (Anethumgraveolens L.) Plant on Oxidative Stress Parameters of Liver Enzymes in Male Rats

Abstract

This the study carried out inextracting of Anethum graveolensL. (dill) volatile oils belong to umbelliferae family and determent percentage of the oils, phytochemical screen were performed A. graveolens volatile oils extract and displayed positive results for Saponin, Cumarins, Phenol, Glycoside, Alkaloid and Flavonoid while Tannins negative results. and determent their impact oxidative stress Malonaldehyde and Lipid peroxidation level, the animal were divide in to five groups, each of which include three animals, the first groups was control groups, the second groups was injection with A. graveolensL. oils extract at a concentration of 25%mg/kg body weight (B.W), the third groups was injected with concentration of 50 mg/kg (B.W), the fourth groups was injected with concentration of 100 mg/kg (B.W) and five groups was injected with concentration of 200 mg/kg (B.W), was injected 7 days and 14 days and blood bled 30 days, the criteria foe stress (MDA and LPO) were defined to establish the effective duration and concentration, indicate the results the groups (G2, G3, G4 and G5) of male rats displayed significantly decline in MDA level (1.96, 2.52, 1.34 and 1.00μmol/L) respectively in comparison with control 2.47μmol/L at the 7th day, G2, G3, G4, and G5 showed a considerable drop by day 14, however. (2.38, 1.93, 1.62 and 1.06μmol/L) respectively in comparison with control 2.46μmol/L. While resultsLPO levels declined significantly in male rat groups (G2, G3, G4, and G5) (17.14, 13.4, 11.53 and 9.35μmol/L) respectively in comparison with control 22.01μmol/L at the 7th day, while at the 14th day (G2,G3,G4 and G5) showed significantly decrease (25.05, 20.94, 18.73, 10.65 and 11.85μmol/L) respectively compared with control 25.05μmol/L. aim from this research is known protective role and antioxidant for dill volatile oil extract.