Study of the Antibiotic Resistance Profile of Klebsiella Pneumonia in Patients Infected with Covid- 19

Abstract

Antimicrobial resistance (AMR) is a global public health challenge. AMR is the ability of a microorganism to resist antimicrobial attack, which in turn prevents successful treatment of an infection. Massive antibiotic therapy has led to an increase in the antibiotic resistance of pathogens of infectious diseases. The problem of antibiotic resistance is especially acute in the treatment of nosocomial infections. Nosocomial infections also called “hospital-acquired infections”, are infections acquired during hospital care which are not present or incubating at admission. Infections occurring more than 48 hours after admission are usually considered nosocomial. The main reason for the prolonged hospitalization of patients infected with COVID-19 is to internal infections of the hospital and complications caused by their influence. it was important to determine the bacterial spectrum of etiological agents of nosocomial infections in patients infected with COVID-19 and the profile of antibiotic resistance. The research materials were collected at the different hospital resuscitations from patients undergoing treatment for a long time and who were resistant to antibiotics. As the resalts showed the highest resistance to amp/sulbactam, Aztreonam, ampicillin, meropenem, moxifloxacin, cefepime, ceftazidime, cefotaxime, ciprofloxacin Levofloxacin, amox/clavulanate, norfloxacin, pip/tazobactam, ceftriaxone was detected in 100 %, resistance to cefoxitin, trim/sulfa and amikacin in 90%, resistance to tobramycin in 80%, and the relatively low resistance was detected to gentamycin in 20 %.